Block System Functionalities


Hello there,
I have a question that can sound strange but I am working on a lock screen using electron to replace the system lock screen. And I was wondering if it is possible with electron to block some system functionalities like the explorer on windows (win32).
The biggest issue is that, even with the lock screen up and running, an aware user can use Ctrl+Alt+Del on windows to open the task manager and close the locker bypassing it without any password or use Alt+Tab to browse open windows.

Is there a way to block that behavior?
Thanks for your help.